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Wednesday 26 April 2017

2017-04-26

[N] AMERI didn’t pay us per diem – Addison Committee
[N] Akufo-Addo to name MMDCE nominees today
[N] Jail Ibrahim Mahama - Lawyer Kwame Adofo
[N] National Security unaware of raid at Nii Lantey Vanderpuye's house - Wife of MP
[N] Soldiers deployed as NPP men vandalise Zebilla MP’s residence
[N] Mahama not sabotaging 'Free SHS' - Bawa Mogtari
[N] Army chief suspended over ‘galamsey’

2017-04-25

[N] Suspect smears himself with faeces to avoid trial
[N] Government is witch-hunting Ibrahim – NDC
[N] Ibrahim Mahama warned GRA not to withdraw cheques - Amaliba
[N] Ibrahim Mahama closed his accounts after issuing the cheques – GRA insists
[N] TMA Engineer faces possible sanctions over GHC80,000 fraud case
[N] Fire is not candle to be blown off easily – GNFS rubbishes criticisms
[N] Illegal miners in Tarkwa promise to show MP 'pepper' for planning to stop galams
[A] Court orders arrest of musician
[N] Court prosecutes landlords without toilet facilities
[N] Work to resume at Kumasi Military hospital
[N] Best snacks for people with type 2 diabetes
[N] EOCO probes customs over Ibrahim Mahama's 44 dud cheques
[N] Is Nana Addo learning incompetence from Rawlings, Mahama? - Kwesi Pratt asks

2017-04-24

[N] 2 Ghanaian workers arrested for killing Chinese employer
[N] Ken Agyapong is unable to insult me because I saved his life – Ephson
[N] NAGRAT to sue gov't over withholding salaries of 26,000 teachers
[N] GRA to confiscate Mahama’s assets over Gh˘10m debt
[N] Miners to hold meeting in Kumasi
[N] Minister on right course with ‘galamsey’ directive - Joyce Aryee
[N] Residents call on gods of Bole to strike Kennedy Agyepong to death
[N] Amewu orders removal of excavators from mining sites
[N] Amewu sacks 9 mine inspectors
[N] EOCO probes GRA over Ibrahim Mahama’s dud cheques
[N] The 21-day #stopGalamseynow ultimatum story
[N] April has been the most difficult for me - Dr Nduom
[N] Regency Hotel fire: Firemen feared for their lives – Keelson
[N] Fake degrees, certificates flood presidency

2017-04-21

[N] EOCO asks Ibrahim Mahama to pay GHC 12.7m
[N] Ignorant Minority must read – Bawumia
[N] Boy, 5, attempts poisoning 6-month-old brother
[N] We’ll not allow Galamsey to destroy our nation – Nana Addo
[N] Did John Mahama teach Nana Addo what Patriotism is all about? - Brogya Gyamfi
[N] Nkonya killings will be treated as a criminal matter – Minister
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International

[ 2017-04-20 ]

Drug given to pregnant women causes 'serious malformations'
Mothers treated with valproate for epilepsy were
up to four times likelier to give birth to a
malformed child, the preliminary study found.

Introduced in France in 1967, valproate is
prescribed widely worldwide.

Doctors in France are now advised not to give it
to girls, women of childbearing age and pregnant
women.

The drug's manufacturer, Sanofi, responded in a
statement that it had been "totally transparent
with health authorities".

"We are aware of the painful situation confronting
the families of children showing difficulties that
may have a link with the anti-epileptic treatment
of their mother during pregnancy," it said.

Some of those affected say France and the company
were too slow to warn of side-effects.

The risk of birth defects associated with
valproate, marketed as Epilim, Depakine, Depakote
and Stavzor among other names, has been known
since the 1980s, especially for spina bifida.

In the UK, the National Health Service (NHS)
issued an alert earlier this month saying
valproate should only be given to girls and women
of childbearing age under specialist supervision
and only when other medications had been found not
to work.

'Very high'
According to the new report (in French) by
France's National Agency for the Safety of
Medicines (ANSM), between 2,150 and 4,100 children
suffered severe malformations linked to the drug.

"The study confirms the highly teratogenic
[capable of causing birth defects] nature of
valproate," Mahmoud Zureik, ANSM's scientific
director and co-author of the report, told AFP
news agency.

"The figure of about 3,000 severe malformations is
very high."

Types of birth defects attributed to the drug
include spina bifida - which occurs when a section
of the spinal column does not form properly - and
defects of the heart and genital organs.

The risk of autism and developmental problems was
also found to be higher, and will be explored in a
follow-up report due later this year.

Women treated for bipolar disorder were at a lower
risk than those treated for epilepsy, the study
found, but were still twice as likely to give
birth to children with major birth defects.

According to ANSM, this is because women treated
for bipolar disorder were less exposed to the
drug.

In its alert issued on 6 April, the NHS noted that
valproate was an "effective medication used to
treat epilepsy and bipolar disorder" but added
that it was also aware of its "off-label" use to
treat migraine or chronic pain.

Lawsuit



Some families of children with birth defects born
to women who took the drug while pregnant -
grouped under an umbrella association known
as APESAC (in French) - have sued Sanofi, saying
that it did not adequately warn about the risks.


"The number of victims is potentially huge,"
APESAC president Marine Martin told AFP.


"We need to take into account children with
malformations and autism, as well as families that
lost a baby due to treatment during pregnancy."


Ms Martin says two of her children, a girl and a
boy, suffered physical defects brought on by
valproate.


French MP Gerard Bapt welcomed the report.


"It now appears fundamental that valproate in all
its forms should not be prescribed for women of
child-bearing age," he said.


Medically necessary exceptions, he added, should
be rare and accompanied by "mandatory
contraceptive use".

Source - BBC



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